Experimental study on peripheral arterial autograft and homograft with autogenous and homologous
artery and vein was carried out to evaluate the patency related with histopathologic findings, during
the period of one to four months after grafting.
Grafts, which were obtained from canine femoral artery and vein in a length of 1∼3㎝, were
anastomosed to replace the resected contralateral or ipisilateral femoral artery of the same dog or
others.
Femoral arteriography at the site of graft, macroscopic and microscopic study were done one to
four months after grafting.
Ⅰ) Patency of the graft by femoral arteriography revealed about 80% of rate.
Highest in autogenous artery grafting group and lowest in homologous vein grafting group. Some
arteriogram revealed slight to moderate degree of constriction and narrowing at the site of anastom
osis and smoe revelaed aneurysmal dilatation of the grafts.
Ⅱ) Microscopic findings of the grafts.
1) Tissue viability of the grafts were evident in all group even in some failure cases, and none of
cases revealed the evidence of histologic rejection phenomenon.
2) Fiber continuity of the grafts were apparently preserved in most of all cases.
3) Fibroblast arrangement in pseudo-intima appeared irregular in cases sacrificed within 2 months
group, regardless of the type grafted, whereas tended to be regular in cases of longer survivals.(more
than 3 months group)
4) Even and smooth pseudo-intima formation was demonstrable in order of autogenous artery
grafting, homologous artery grafting, autogenous vein grafting and then homologous vein grafting
group.
Pseudo-intima formation tended to localize near the anastomosis in shorter survival group, especially
in vein grafting group, regardless of the autogenous or homologous.
5) Elastic fibers were more or less well preserved in autogenous group than those of homologous
group.
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